The Department of Pathology and Cell Biology at Columbia University Irving Medical Center seeks a highly qualified individual to perform computational and statistical research relating to the formation and maintenance of immunological memory, with specific focus on T cells. The candidate will work under the direct supervision of Dr Andrew Yates, and will display an aptitude for both quantitative analysis and an enthusiasm for understanding the intricacies of both mouse and human immunology.

At CUIMC, we stand together because diverse experiences, perspective, and values enrich every dimension of our work. Join our team and see how your unique skills and experiences can create a real impact by changing lives.

Job Function:

• Write code in R, Python, and/or C to analyse data from our experimental collaborators
• Formulate and encode mathematical models that describe these data
• Perform inference to fit models to data, preferably with Bayesian approaches, and making use of our high-performance computing cluster
• Take initiative in guiding the direction of their research where appropriate
• Prepare manuscripts for publication
• Actively participate in group discussions and journal clubs
• Present their work at national and/or international conferences

Lab Mission/Purpose:

T and B lymphocytes are key components of vertebrate immune systems. They form richly structured and highly interactive communities that provide protection against infection while maintaining tolerance to innocuous antigens. They also encode immunological memory, responding rapidly and potently to previously encountered antigens. Our research integrates theoretical and computational tools with more traditional experimental approaches to study multiple aspects of lymphocyte dynamics. Our aim is to develop a mechanistic understanding of the rules underlying lymphocyte development, homeostasis, and their trajectories in response to antigen challenge. Our philosophy is to confront and break models with data to search for robust and quantitative explanations of immunological phenomena. Our current interests relate to the population dynamics of circulating lymphocytes, with particular focus on the impact of age on their persistence and function; and the ecology of tissue-resident memory T cells.

Minimum Education Requirements:

Bachelors degree or equivalent in mathematics, mathematical biology, theoretical biology, or similar

Minimum Skills Required:

• Competent to a high standard in computer programming
• Undergraduate level calculus and statistics
• Able to demonstrate advanced understanding of T cell biology

Preferred Qualifications:

Undergraduate or graduate level training in basic immunology.

Columbia University is an Equal Opportunity Employer / Disability / Veteran

Pay Transparency Disclosure

The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

Equal Opportunity Employer / Disability / Veteran

Columbia University is committed to the hiring of qualified local residents.

Minimum Salary: 31200.00 Maximum Salary: 31200.00 Salary Unit: Yearly