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Columbia University Postdoctoral Research Scientist (Wu Lab) in New York, New York

Posting Details

First Section

Job Requisition Number 0000952

Field(s) of Specialization Vascular system and anomalies

Position Title Postdoctoral Research Scientist (Wu Lab)

Department SRG Surgery

Division Surgery

Location Medical Center

Summary Description

The Department of Surgery at Columbia University Vagelos College of Physicians and Surgeons is accepting applications for a Postdoctoral Research Scientist in the DOD-funded laboratory of Dr. June Wu. We are seeking a highly motivated individual to join a research team working together to understand the development of the vascular system and the genetic causes of vascular anomalies. The research will involve recombinant DNA work, protein evaluation and purification, viral vector construction and use, in vitro angiogenesis assays, murine xenograft and transgenic mouse modeling. Responsibilities include: Perform laboratory research in the area of vascular biology, vascular development using human-derived tissues and cells. Evaluate the effect of small molecule compounds on vascular tumor and malformation-derived cell function including proliferation, migration, differentiation, vasculogeneiss and angiogenesis (in vitro).Using a xenograft mouse model to assess in vivo effects of small molecular compounds on pathogenesis of vascular anomalies.Interact with the High Throughput Screening core facilities to design large format templates for high throughput drug and small molecule compounds screening. Interact with Institute of Genomic Medicine (IGM) and whole exome sequencing team; analysis of genetic data. Maintain and analyze a transgenic mouse model of venous malformation (with technician help) Quantitatively analyze and summarize research data sets utilizing statistical methods. Present research results and prepare manuscripts for peer review and publication in professional journals. Perform literature searches, manage data, analyze experimental results and published data. Participate to the development of an extramurally funded research program by assisting PIs with NIH grants by developing and generating data and figures.

Minimum Degree Required

PhD or MD with experience in molecular biology techniques (protein work/immunoblotting, cell culture, mouse modeling experience).

Minimum Qualifications

Those with experience using transgenic mouse models with a background in molecular biology, vascular biology, and/or genetics are encouraged to apply.

Preferred Qualifications

Strong knowledge of current concepts of molecular oncology, expertise in both vascular and molecular biology preferred, motivated and creative individuals with a commitment to academic research who can work independently as well as in team-based projects and excellent communication skills.

Additional Information

RAPS posting date 08/06/2019

Search Closing Date

Special Instructions to the Applicant

Proposed Start Date 08/15/2019

EEO Statement

Columbia University is Equal Opportunity Employer / Disability / Veteran

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Documents Needed to Apply

Required Documents

  • Curriculum Vitae

Optional Documents